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can lead to encrustation and obstruction of the catheter .   Treating ASB is not recommended because it does not
                                                        34
          Individuals with catheters most commonly harbor E. coli, En-  reduce the frequency of UTIs and can lead to reinfections
          terococcus faecalis, and Proteus mirabilis. Additionally, urea-  with resistant bacteria . The optimal choice of therapy does
                                                                               37
          se-producing bacteria such as Proteus mirabilis, Morganella   not  differ  from  patients  without  catheters  (Table  1).  Tre-
          morganii, Klebsiella pneumoniae, and Providencia stuartii are   atment should last for seven days if there is a rapid respon-
          frequently  encountered .  Proteus mirabilis  is  particularly   se to therapy. Prolonged treatment leads to more frequent
                             34
          active  in  biofilm  and  crystalline  biofilm  formation  and  is   adverse effects. The benefit of removing the catheter before
          responsible for approximately 80% of all catheter obstructi-  starting therapy is reflected in reduced relapses and a re-
          ons .                                              duction in the number of bacteria remaining in the biofilm.
             35
             The  clinical  presentation  of  symptomatic  infection  in   Prevention of infections associated with indwelling cat-
          individuals  with  catheters  most  commonly  involves  high   heters  is  included  in  existing  recommendations 38,  39 .  The
          fever without local genitourinary symptoms . In some pa-  most important thing is to reduce the use of catheters or
                                              23
          tients, pain and tenderness in the costovertebral area, cat-  use  them  for  as  short  a  time  as  possible.  Some  authors
          heter obstruction, or hematuria may occur. The consensus   also recommend external, condom catheters, which carry
          regarding initiating empirical antibiotic therapy implies the   a lower risk of infection . Special attention should be paid
                                                                                40
          presence of one of the following symptoms: high fever, new   to non-traumatic catheter placement to prevent bleeding,
          costovertebral angle tenderness, new-onset delirium, or the   which predisposes to infection. It is important to promptly
          absence of an alternative source of infection .    recognize obstruction and replace the catheter. Special cat-
                                             36
                                                             heters impregnated with antimicrobial agents or drainage
             It is advisable to take a sample with a new catheter when   bags with antiseptics do not seem to have met expectations
          the finding is exclusively from urine, not from the biofilm,   in terms of reducing infection rates . During catheter re-
                                                                                           41
          and a count higher than 10 CFU/mL is considered relevant   placement, transient bacteremia may occur, which does not
          for defining bacteriuria. Additionally, it is recommended to   have serious consequences, so antimicrobial prophylaxis is
          initiate  therapy  only  after  replacing  the  catheter  if  it  has   not recommended during catheter replacement.
          been in place for more than two weeks .
                                         38


          Conclusion

          In elderly individuals, there is a high prevalence of asymptomatic bacteriuria and urinary tract
          infections. Asymptomatic bacteriuria does not require treatment except before urological surgical
          procedures. The diagnosis of symptomatic infections is often overdiagnosed, leading to antibiotic
          overuse and reinfection with resistant microorganisms.


          In individuals residing in care facilities, distinguishing between asymptomatic bacteriuria (ASB)

          and urinary tract infection (UTI) is not easy due to the unreliability and nonspecificity of symptoms.
          Individuals with indwelling urinary catheters are at increased risk for UTIs, and special diagnostic,
          therapeutic, and preventive strategies are applied for them.




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          52     DOI: 10.5937/Galmed2409055D
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